Endotoxin, tumor necrosis factor, and interleukin-1 decrease hepatic squalene synthase activity, protein, and mRNA levels in Syrian hamsters

Recent studies have shown that endotoxin (LPS) administration to Syrian hamsters markedly increased hepatic HMG-CoA reductase activity, protein mass, and mRNA levels, but only produced a modest increase in hepatic cholesterol synthesis, suggesting that LPS may also influence other key enzymes involv...

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Bibliografiske detaljer

Principais autores:	R A Memon, I Shechter, A H Moser, J K Shigenaga, C Grunfeld, K R Feingold
Format:	Artigo
Sprog:	Inglês
Udgivet:	Elsevier 1997-08-01
Serier:	Journal of Lipid Research
Online adgang:	http://www.sciencedirect.com/science/article/pii/S0022227520371807
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