Development of a Cost-Effective Process for the Heterologous Production of SARS-CoV-2 Spike Receptor Binding Domain Using <i>Pichia pastoris</i> in Stirred-Tank Bioreactor

SARS-CoV-2 was identified as the pathogenic agent causing the COVID-19 pandemic. Among the proteins codified by this virus, the Spike protein is one of the most-external and -exposed. A fragment of the Spike protein, named the receptor binding domain (RBD), interacts with the ACE2 receptors of human...

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Principais autores:	Diego G. Noseda, Cecilia D’Alessio, Javier Santos, Tommy Idrovo-Hidalgo, Florencia Pignataro, Diana E. Wetzler, Hernán Gentili, Alejandro D. Nadra, Ernesto Roman, Carlos Paván, Lucas A. M. Ruberto
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2023-05-01
coleção:	Fermentation
Assuntos:	SARS-CoV-2 RBD antigen STBR <i>Pichia pastoris</i>
Acesso em linha:	https://www.mdpi.com/2311-5637/9/6/497
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