Saccharomyces cerevisiae Differential Functionalization of Presumed ScALT1 and ScALT2 Alanine Transaminases Has Been Driven by Diversification of Pyridoxal Phosphate Interactions

Saccharomyces cerevisiae arose from an interspecies hybridization (allopolyploidiza-tion), followed by Whole Genome Duplication. Diversification analysis of ScAlt1/ScAlt2 indicated that while ScAlt1 is an alanine transaminase, ScAlt2 lost this activity, constituting an example in which one of the me...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Erendira Rojas-Ortega, Beatriz Aguirre-López, Horacio Reyes-Vivas, Martín González-Andrade, Jose C. Campero-Basaldúa, Juan P. Pardo, Alicia González
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2018-05-01
coleção:	Frontiers in Microbiology
Assuntos:	paralogous genes pyridoxal phosphate binding alanine transaminases functional diversification structural organization alanine metabolism
Acesso em linha:	http://journal.frontiersin.org/article/10.3389/fmicb.2018.00944/full
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!