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The landscape of expression and alternative splicing variation across human traits

Summary: Understanding the consequences of individual transcriptome variation is fundamental to deciphering human biology and disease. We implement a statistical framework to quantify the contributions of 21 individual traits as drivers of gene expression and alternative splicing variation across 46...

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Principais autores: Raquel García-Pérez, Jose Miguel Ramirez, Aida Ripoll-Cladellas, Ruben Chazarra-Gil, Winona Oliveros, Oleksandra Soldatkina, Mattia Bosio, Paul Joris Rognon, Salvador Capella-Gutierrez, Miquel Calvo, Ferran Reverter, Roderic Guigó, François Aguet, Pedro G. Ferreira, Kristin G. Ardlie, Marta Melé
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2023-01-01
Serier:Cell Genomics
Fag:
transcriptome
ancestry
sex
age
BMI
diabetes
Online adgang:http://www.sciencedirect.com/science/article/pii/S2666979X22002075
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