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Epigenetic age-predictor for mice based on three CpG sites

Epigenetic clocks for mice were generated based on deep-sequencing analysis of the methylome. Here, we demonstrate that site-specific analysis of DNA methylation levels by pyrosequencing at only three CG dinucleotides (CpGs) in the genes Prima1, Hsf4, and Kcns1 facilitates precise estimation of chro...

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Autori principali: Yang Han, Monika Eipel, Julia Franzen, Vadim Sakk, Bertien Dethmers-Ausema, Laura Yndriago, Ander Izeta, Gerald de Haan, Hartmut Geiger, Wolfgang Wagner
Natura: Artigo
Lingua:Inglês
Pubblicazione: eLife Sciences Publications Ltd 2018-08-01
Serie:eLife
Soggetti:
aging
age
clock
DNA methylation
predictor
signature
Accesso online:https://elifesciences.org/articles/37462
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