Drug resistance analysis by next generation sequencing in Leishmania

The use of next generation sequencing has the power to expedite the identification of drug resistance determinants and biomarkers and was applied successfully to drug resistance studies in Leishmania. This allowed the identification of modulation in gene expression, gene dosage alterations, changes...

Description complète

Détails bibliographiques

Auteurs principaux:	Philippe Leprohon, Christopher Fernandez-Prada, Élodie Gazanion, Rubens Monte-Neto, Marc Ouellette
Format:	Artigo
Langue:	Inglês
Publié:	Elsevier 2015-04-01
Collection:	International Journal for Parasitology: Drugs and Drug Resistance
Sujets:	Leishmania Genome Next generation sequencing Drug resistance Aneuploidy Single nucleotide polymorphisms Gene amplification
Accès en ligne:	http://www.sciencedirect.com/science/article/pii/S2211320714000281
Tags:	Ajouter un tag Pas de tags, Soyez le premier à ajouter un tag!