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Multiregional transcriptomics identifies congruent consensus subtypes with prognostic value beyond tumor heterogeneity of colorectal cancer

Abstract Intra-tumor heterogeneity compromises the clinical value of transcriptomic classifications of colorectal cancer. We investigated the prognostic effect of transcriptomic heterogeneity and the potential for classifications less vulnerable to heterogeneity in a single-hospital series of 1093 t...

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Egile Nagusiak: Jonas Langerud, Ina A. Eilertsen, Seyed H. Moosavi, Solveig M. K. Klokkerud, Henrik M. Reims, Ingeborg F. Backe, Merete Hektoen, Ole H. Sjo, Marine Jeanmougin, Sabine Tejpar, Arild Nesbakken, Ragnhild A. Lothe, Anita Sveen
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Portfolio 2024-05-01
Saila:Nature Communications
Sarrera elektronikoa:https://doi.org/10.1038/s41467-024-48706-2
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