Establishment of a 3D Multicellular HCC Tumor Spheroid Model to Unravel Nrf2’s Influence on the Tumor Immune Microenvironment

Hepatocellular carcinoma (HCC) remains a leading cause of cancer-related death, yet adequate <i>in vitro</i> models mimicking the tumor immune microenvironment (TIME) are rare. Specifically, the role of the transcription factor nuclear factor erythroid 2-related factor 2 (Nrf2) in modulating interac...

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Hauptverfasser:	Nicole Böttcher, Philipp Krumm, Rosanna Huchzermeier, Lara Berschkeit, Johanna Vollmer, Julie Dick, Thomas Pufe, Athanassios Fragoulis
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	MDPI AG 2026-03-01
Schriftenreihe:	Bioengineering
Schlagworte:	Nrf2 spheroid multicellular tumor spheroid HCC N-HCC25 tumor associated macrophages
Online-Zugang:	https://www.mdpi.com/2306-5354/13/3/336
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