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Genetic variants in ER cofactor genes and endometrial cancer risk.

Given that the transcriptional regulatory activity of estrogen receptor (ER) is modulated by its biochemical cofactors, genetic variation within the ER cofactor genes may alter cellular response to estrogen exposure and consequently modify the risk for endometrial cancer. We genotyped 685 tagging SN...

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Autori principali: Yuqing Li, Hui-Qi Low, Jia Nee Foo, Hatef Darabi, Kristjana Einarsdόttir, Keith Humphreys, Amanda Spurdle, ANECS Group, Douglas F Easton, Deborah J Thompson, Alison M Dunning, Paul D P Pharoah, Kamila Czene, Kee Seng Chia, Per Hall, Jianjun Liu
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science (PLoS) 2012-01-01
Serie:PLoS ONE
Accesso online:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0042445&type=printable
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