Comparisons of biophysical properties and bioactivities of mono-PEGylated endostatin and an endostatin analog
Abstract Background Endostatin (ES) is a well-established potent endogenous antiangiogenic factor. An ES variant, called zinc-binding protein-ES (ZBP-ES), is clinically available; however, its use is limited by rapid renal clearance and short residence time. PEGylation has been exploited to overcome...
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| Principais autores: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BMC
2016-01-01
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| coleção: | Chinese Journal of Cancer |
| Assuntos: | |
| Acesso em linha: | http://link.springer.com/article/10.1186/s40880-016-0080-8 |
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