Quantitative Simulations Predict Treatment Strategies Against Fungal Infections in Virtual Neutropenic Patients

The condition of neutropenia, i.e., a reduced absolute neutrophil count in blood, constitutes a major risk factor for severe infections in the affected patients. Candida albicans and Candida glabrata are opportunistic pathogens and the most prevalent fungal species in the human microbiota. In immuno...

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Autores principales:	Sandra Timme, Teresa Lehnert, Maria T. E. Prauße, Kerstin Hünniger, Ines Leonhardt, Oliver Kurzai, Marc Thilo Figge
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Frontiers Media S.A. 2018-04-01
Colección:	Frontiers in Immunology
Materias:	fungal infections neutropenia treatment strategies bottom-up modeling approach computer simulations
Acceso en línea:	http://journal.frontiersin.org/article/10.3389/fimmu.2018.00667/full
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