Acetylation of Lysine 243 Inhibits the oriC Binding Ability of DnaA in Escherichia coli

DNA replication initiation is a central event in the cell cycle, and it is strictly controlled by multiple regulatory mechanisms. Our previous work showed that acetylation of residue lysine (K) 178 prevents DnaA from binding to ATP, which leads to the inhibition of DNA replication initiation. Here,...

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Principais autores:	Yu-Feng Yao, Shuxian Li, Qiufen Zhang, Zhihong Xu
Format:	Artigo
Jezik:	Inglês
Izdano:	Frontiers Media S.A. 2017-04-01
Serija:	Frontiers in Microbiology
Teme:	lysine acetylation replication initiation initiator DnaA acetyl-phosphate Escherichia coli
Online dostop:	http://journal.frontiersin.org/article/10.3389/fmicb.2017.00699/full
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