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Targeting of Protein Kinase CK2 in Acute Myeloid Leukemia Cells Using the Clinical-Grade Synthetic-Peptide CIGB-300

Protein kinase CK2 has emerged as an attractive therapeutic target in acute myeloid leukemia (AML), an advent that becomes particularly relevant since the treatment of this hematological neoplasia remains challenging. Here we explored for the first time the effect of the clinical-grade peptide-based...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Mauro Rosales, George V. Pérez, Ailyn C. Ramón, Yiliam Cruz, Arielis Rodríguez-Ulloa, Vladimir Besada, Yassel Ramos, Dania Vázquez-Blomquist, Evelin Caballero, Daylen Aguilar, Luis J. González, Katharina Zettl, Jacek R. Wiśniewski, Ke Yang, Yasser Perera, Silvio E. Perea
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI AG 2021-07-01
Schriftenreihe:Biomedicines
Schlagworte:
protein kinase CK2
acute myeloid leukemia
CIGB-300
phosphoproteomics
Online-Zugang:https://www.mdpi.com/2227-9059/9/7/766
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