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A top‐down systems biology view of microbiome‐mammalian metabolic interactions in a mouse model

Abstract Symbiotic gut microorganisms (microbiome) interact closely with the mammalian host's metabolism and are important determinants of human health. Here, we decipher the complex metabolic effects of microbial manipulation, by comparing germfree mice colonized by a human baby flora (HBF) or a no...

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Автори: François‐Pierre J Martin, Marc‐Emmanuel Dumas, Yulan Wang, Cristina Legido‐Quigley, Ivan K S Yap, Huiru Tang, Séverine Zirah, Gerard M Murphy, Olivier Cloarec, John C Lindon, Norbert Sprenger, Laurent B Fay, Sunil Kochhar, Peter van Bladeren, Elaine Holmes, Jeremy K Nicholson
Формат: Artigo
Мова:Inglês
Опубліковано: Springer Nature 2007-05-01
Серія:Molecular Systems Biology
Предмети:
co‐metabolism
gut microflora
metabonomics/metabolomics
network modeling
systems biology
Онлайн доступ:https://doi.org/10.1038/msb4100153
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