Mechanism of EHMT2-mediated genomic imprinting associated with Prader-Willi syndrome

Abstract Prader-Willi Syndrome (PWS) is caused by the loss of expression of paternally expressed genes in the human 15q11.2-q13 imprinting domain. A set of imprinted genes that are active on the paternal but silenced on the maternal chromosome are intricately regulated by a bipartite imprinting cent...

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Hlavní autoři:	Sung Eun Wang, Yubao Cheng, Jaechul Lim, Mi-Ae Jang, Emily N. Forrest, Yuna Kim, Meaghan Donahue, Sungsin Jo, Sheng-Nan Qiao, Dong Eun Lee, Jun Young Hong, Yan Xiong, Jian Jin, Siyuan Wang, Yong-hui Jiang
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Nature Portfolio 2025-07-01
Edice:	Nature Communications
On-line přístup:	https://doi.org/10.1038/s41467-025-61156-8
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