Megakaryocytic potentiating factor and mature mesothelin stimulate the growth of a lung cancer cell line in the peritoneal cavity of mice.

The mesothelin (MSLN) gene encodes a 71 kilodalton (kDa) precursor protein that is processed into megakaryocytic potentiating factor (MPF), a 31 kDa protein that is secreted from the cell, and mature mesothelin (mMSLN), a 40 kDa cell surface protein. The mMSLN binds to CA125, an interaction that has...

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Detalhes bibliográficos

Principais autores:	Jingli Zhang, Tapan K Bera, Wenhai Liu, Xing Du, Christine Alewine, Raffit Hassan, Ira Pastan
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Public Library of Science (PLoS) 2014-01-01
Colecção:	PLoS ONE
Acesso em linha:	http://europepmc.org/articles/PMC4132110?pdf=render
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