Identifying nexilin as a central gene in neutrophil-driven abdominal aortic aneurysm pathogenesis

Abstract Objectives Abdominal aortic aneurysm (AAA) is an inflammation-driven disease in which neutrophil infiltration is critical to its progression. This study aims to explore the molecular mechanisms behind neutrophil infiltration in AAA and identify key regulatory genes. Methods We utilized weig...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Bohan Yang, Yiyan Xu, Fengfei Yan, Cheng Peng, Ye Song, Song Han, Haiyang Wang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2025-03-01
coleção:	Molecular Medicine
Assuntos:	Abdominal aortic aneurysm Neutrophils Weighted gene co-expression network analysis Nexilin Immune cell infiltration Machine learning
Acesso em linha:	https://doi.org/10.1186/s10020-025-01157-x
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!