Polygenic risk scores for prostate cancer: Comparative evaluations in UK and Australian cohorts

Summary: Risk-based approaches offer promise for enhancing early detection of prostate cancer. Polygenic risk scores (PGSs) have emerged as a potential approach for risk stratification, though their performance varies by population. We evaluated nine PGSs (four existing, five new) for predicting 5-y...

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Hlavní autoři:	Hamzeh M. Tanha, Matthew H. Law, Nathan Ingold, Philip Ly, Catherine M. Olsen, Nirmala Pandeya, David P. Smith, Robert J. MacInnis, David C. Whiteman, Anne E. Cust, Julia Steinberg
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Elsevier 2025-10-01
Edice:	HGG Advances
Témata:	age-specific risk Australia cohort study genomic risk score polygenic risk score prostate cancer
On-line přístup:	http://www.sciencedirect.com/science/article/pii/S2666247725000806
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