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Monocyte proinflammatory phenotypic control by ephrin type A receptor 4 mediates neural tissue damage

Circulating monocytes have emerged as key regulators of the neuroinflammatory milieu in a number of neuropathological disorders. Ephrin type A receptor 4 (Epha4) receptor tyrosine kinase, a prominent axon guidance molecule, has recently been implicated in the regulation of neuroinflammation. Using a...

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Principais autores: Elizabeth A. Kowalski, Eman Soliman, Colin Kelly, Erwin Kristobal Gudenschwager Basso, John Leonard, Kevin J. Pridham, Jing Ju, Alison Cash, Amanda Hazy, Caroline de Jager, Alexandra M. Kaloss, Hanzhang Ding, Raymundo D. Hernandez, Gabe Coleman, Xia Wang, Michelle L. Olsen, Alicia M. Pickrell, Michelle H. Theus
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical investigation 2022-08-01
coleção:JCI Insight
Assuntos:
Neuroscience
Acesso em linha:https://doi.org/10.1172/jci.insight.156319
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