Cell‐free chromatin immunoprecipitation can determine tumor gene expression in lung cancer patients
Cell‐free DNA (cfDNA) in blood plasma can be bound to nucleosomes that contain post‐translational modifications representing the epigenetic profile of the cell of origin. This includes histone H3 lysine 36 trimethylation (H3K36me3), a marker of active transcription. We hypothesised that cell‐free ch...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Wiley
2023-05-01
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| Schriftenreihe: | Molecular Oncology |
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| Online-Zugang: | https://doi.org/10.1002/1878-0261.13394 |
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