N-substituted benzyl matrinic acid derivatives inhibit hepatitis C virus (HCV) replication through down-regulating host heat-stress cognate 70 (Hsc70) expression.

Heat-stress cognate 70 (Hsc70) is a host factor that helps hepatitis C virus (HCV) to complete its life cycle in infected hepatocytes. Using Hsc70 as a target for HCV inhibition, a series of novel N-substituted benzyl matrinic/sophoridinic acid derivatives was synthesized and evaluated for their ant...

Повний опис

Бібліографічні деталі

Автори:	Na-Na Du, Zong-Gen Peng, Chong-Wen Bi, Sheng Tang, Ying-Hong Li, Jian-Rui Li, Yan-Ping Zhu, Jing-Pu Zhang, Yan-Xiang Wang, Jian-Dong Jiang, Dan-Qing Song
Формат:	Artigo
Мова:	Inglês
Опубліковано:	Public Library of Science (PLoS) 2013-01-01
Серія:	PLoS ONE
Онлайн доступ:	http://europepmc.org/articles/PMC3597726?pdf=render
Теги:	Додати тег Немає тегів, Будьте першим, хто поставить тег для цього запису!