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Codevelopment of gut microbial metabolism and visual neural circuitry over human infancy

ABSTRACT Infancy is a time of elevated neuroplasticity supporting rapid brain and sensory development. The gut microbiome, also undergoing extensive developmental changes in early life, may influence brain development through the metabolism of neuroactive compounds. Here, we leverage longitudinal da...

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Auteurs principaux: Kevin S. Bonham, Emma T. Margolis, Guilherme Fahur Bottino, Ana C. Sobrino, Fadheela Patel, Shelley McCann, Michal R. Zieff, Marlie Miles, Donna Herr, Lauren Davel, Cara Bosco, Curtis Huttenhower, Nicolò Pini, Daniel C. Alexander, Derek K. Jones, Steve C. R. Williams, Dima Amso, Melissa Gladstone, William P. Fifer, Kirsten A. Donald, Laurel J. Gabard-Durnam, Vanja Klepac-Ceraj
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2025-08-01
Collection:mBio
Sujets:
visual cortex development
metagenome
infant gut microbiome
visual-evoked potential
neuroplasticity
Accès en ligne:https://journals.asm.org/doi/10.1128/mbio.00835-25
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