Regulation of enhanced cerebrovascular expression of proinflammatory mediators in experimental subarachnoid hemorrhage via the mitogen-activated protein kinase kinase/extracellular signal-regulated kinase pathway

<p>Abstract</p> <p>Background</p> <p>Subarachnoid hemorrhage (SAH) is associated with high morbidity and mortality. It is suggested that the associated inflammation is mediated through activation of the mitogen-activated protein kinase (MAPK) pathway which plays a crucial role in the pathogenesis of...

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Główni autorzy:	Maddahi Aida, Povlsen Gro, Edvinsson Lars
Format:	Artigo
Język:	Inglês
Wydane:	BMC 2012-12-01
Seria:	Journal of Neuroinflammation
Hasła przedmiotowe:	Subarachnoid hemorrhage TNFα IL-1β IL-6 MMP-9 Phosphorylated ERK1/2
Dostęp online:	http://www.jneuroinflammation.com/content/9/1/274
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