APOE protects against severe infection with Mycobacterium tuberculosis by restraining production of neutrophil extracellular traps.
Mice lacking apolipoprotein E (APOE, Apoe-/- mice) on a high cholesterol (HC) diet are highly susceptible to infection with Mycobacterium tuberculosis (Mtb) but the underlying immune dysregulation has been unclear. While neutrophils are often the predominant cell type in the lungs of humans with sev...
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| Principais autores: | , , , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Public Library of Science (PLoS)
2025-06-01
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| Serija: | PLoS Pathogens |
| Online dostop: | https://doi.org/10.1371/journal.ppat.1013267 |
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