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Platelet phosphatidylserine is the critical mediator of thrombosis in heparin-induced thrombocytopenia

Heparin-induced thrombocytopenia (HIT) is a severe immune-mediated prothrombotic disorder caused by antibodies (Ab) reactive to complexes of platelet factor 4 and heparin. Platelets (PLT) and their interaction with different immune cells contribute to prothrombotic conditions in HIT. However, the e...

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Bibliografiset tiedot
Päätekijät: Jan Zlamal, Anurag Singh, Karoline Weich, Hisham Jaffal, Günalp Uzun, Lisann Pelzl, Karina Althaus, Tamam Bakchoul
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Ferrata Storti Foundation 2023-04-01
Sarja:Haematologica
Linkit:https://haematologica.org/article/view/11064
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