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Nickel-catalysed migratory hydroalkynylation and enantioselective hydroalkynylation of olefins with bromoalkynes

Chiral alkyne motifs bearing an α stereocentre are often found in many bioactive compounds, chemical probes, and functional materials. Here the authors show NiH-catalysed reductive migratory hydroalkynylation of olefins with bromoalkynes that form benzylic alkynylation products in high yield and wit...

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Autori principali: Xiaoli Jiang, Bo Han, Yuhang Xue, Mei Duan, Zhuofan Gui, You Wang, Shaolin Zhu
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Portfolio 2021-06-01
Serie:Nature Communications
Accesso online:https://doi.org/10.1038/s41467-021-24094-9
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