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Co-evolution of primate SAMHD1 and lentivirus Vpx leads to the loss of the vpx gene in HIV-1 ancestor.

Cross-species transmission and adaptation of simian immunodeficiency viruses (SIVs) to humans have given rise to human immunodeficiency viruses (HIVs). HIV type 1 (HIV-1) and type 2 (HIV-2) were derived from SIVs that infected chimpanzee (SIVcpz) and sooty mangabey (SIVsm), respectively. The HIV-1 r...

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Autors principals: Chiyu Zhang, Suresh de Silva, Jian-Hua Wang, Li Wu
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science (PLoS) 2012-01-01
Col·lecció:PLoS ONE
Accés en línia:http://europepmc.org/articles/PMC3345027?pdf=render
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