Cryptococcus neoformans serotype A virulence and pathogenicity are capsular glucuronoxylomannan (GXM) motif composition dependent

ABSTRACT The Cryptococcus neoformans capsular extracellular polysaccharide (EPS) plays an essential role in virulence and host immunomodulation. In this study, we analyzed the virulence of four serotype A C. neoformans strains with different polysaccharide structures: two multi-motif (H99 and KN99α)...

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Autors principals:	Samuel Rodrigues Dos Santos Junior, Piotr R. Stempinski, Marcelo Valdemir de Araujo, Kevin Rojas, Gracen R. Gerbig, Livia C. Liporagi Lopes, Daniel F. Q. Smith, Maggie P. Wear, Arturo Casadevall
Format:	Artigo
Idioma:	Inglês
Publicat:	American Society for Microbiology 2025-11-01
Col·lecció:	mBio
Matèries:	Cryptococcus neoformans capsular polysaccharide GXM virulence glucuronoxylomannan motifs
Accés en línia:	https://journals.asm.org/doi/10.1128/mbio.02646-25
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