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Introducing tetracycline as a potential OXA-48 carbapenemase inhibitor: an in silico and in vitro approach

Abstract The emergence of OXA-48 carbapenemase has significantly compromised the effectiveness of carbapenems in treating drug-resistant Gram-negative infections, highlighting an urgent need for novel therapeutic strategies due to the limitations of currently available β-lactam inhibitors against th...

Бүрэн тодорхойлолт

-д хадгалсан:
Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид: Hourieh Kalhor, Mana Salehibarmi, Maryam Siroosi
Формат: Artigo
Хэл сонгох:Inglês
Хэвлэсэн: Nature Portfolio 2026-05-01
Цуврал:Scientific Reports
Нөхцлүүд:
Онлайн хандалт:https://doi.org/10.1038/s41598-026-42462-7
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