A novel small RNA PhaS contributes to polymyxin B-heteroresistance in carbapenem-resistant Klebsiella pneumoniae

In recent years, polymyxin has been used as a last-resort therapy for carbapenem-resistant bacterial infections. The emergence of heteroresistance (HR) to polymyxin hampers the efficacy of polymyxin treatment by amplifying resistant subpopulation. However, the mechanisms behind polymyxin HR remain u...

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Detalhes bibliográficos

Principais autores:	Zhiwei Zhao, Tingting Yang, Guoxiu Xiang, Shebin Zhang, Yimei Cai, Guosheng Zhong, Jieying Pu, Cong Shen, Jianming Zeng, Cha Chen, Bin Huang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis Group 2024-12-01
coleção:	Emerging Microbes and Infections
Assuntos:	Klebsiella pneumoniae carbapenem resistance small RNA polymyxin B heteroresistance
Acesso em linha:	https://www.tandfonline.com/doi/10.1080/22221751.2024.2366354
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