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Physiological Adaptations and Serum-Based Biomarker Dynamics During Multimodal Rehabilitation in Chronic Pain: Analysis of a Prospective Cohort Study

Background: Chronic pain is a multifactorial condition for which interdisciplinary multimodal rehabilitation is guideline-recommended, yet the biological mechanisms underlying treatment response remain incompletely understood and validated predictive biomarkers have not been established. Objective:...

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Principais autores: Meike Meinzer, Markus Bassler, Franziska Kessemeier, Corinna Webering, Detlef Neumann, Heike Bähre, Ralf Lichtinghagen, Mathias Rhein, Johannes Achenbach, Christoph Gutenbrunner, Matthias Karst
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2026-06-01
coleção:Biomolecules
Assuntos:
chronic pain
multimodal pain rehabilitation
endocannabinoid system
biomarkers
2-arachidonoylglycerol
treatment response
Acesso em linha:https://www.mdpi.com/2218-273X/16/6/841
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