Landscape mapping of shared antigenic epitopes and their cognate TCRs of tumor-infiltrating T lymphocytes in melanoma

HLA-restricted T cell responses can induce antitumor effects in cancer patients. Previous human T cell research has largely focused on the few HLA alleles prevalent in a subset of ethnic groups. Here, using a panel of newly developed peptide-exchangeable peptide/HLA multimers and artificial antigen-...

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Bibliografiske detaljer

Principais autores:	Kenji Murata, Munehide Nakatsugawa, Muhammed A Rahman, Linh T Nguyen, Douglas G Millar, David T Mulder, Kenji Sugata, Hiroshi Saijo, Yukiko Matsunaga, Yuki Kagoya, Tingxi Guo, Mark Anczurowski, Chung-Hsi Wang, Brian D Burt, Dalam Ly, Kayoko Saso, Alexandra Easson, David P Goldstein, Michael Reedijk, Danny Ghazarian, Trevor J Pugh, Marcus O Butler, Tak W Mak, Pamela S Ohashi, Naoto Hirano
Format:	Artigo
Sprog:	Inglês
Udgivet:	eLife Sciences Publications Ltd 2020-04-01
Serier:	eLife
Fag:	peptide/HLA multimer artificial anitgen-presenting cell melanoma T cell receptor shared antigenic epitope tumor-infiltrating T lymphocyte
Online adgang:	https://elifesciences.org/articles/53244
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