Patient-derived cell lines unveil COL1A2 as a predictor of docetaxel resistance in breast cancer

IntroductionBreast cancer is the most common malignant tumor among women worldwide and a major cause of cancer-related mortality. Chemoresistance presents a significant challenge in breast cancer therapy and is a primary driver of tumor recurrence and metastasis. However, effective predictive strate...

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Hauptverfasser:	Yuwei Gao, Rong Wang, Xiaowei Dou, Song Chen, Wenhao Chen, Jinting Liu, Suo Zhu, Jianjun Huang, Qingjun Gao
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Frontiers Media S.A. 2026-03-01
Schriftenreihe:	Frontiers in Oncology
Schlagworte:	breast cancer HR+/HER2-negative docetaxel resistance patient-derived primary cancer cell lines COL1A2 neoadjuvant chemotherapy
Online-Zugang:	https://www.frontiersin.org/articles/10.3389/fonc.2025.1737405/full
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