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Synovial Fluid Extracellular Vesicles from Patients with Severe Osteoarthritis Differentially Promote a Pro-Catabolic, Inflammatory Chondrocyte Phenotype

Synovial inflammation is recognised as a pathological driver of osteoarthritis (OA), a degenerative joint disease involving cartilage degradation and joint pain. Since extracellular vesicles (EVs) have emerged as key mediators of cellular cross-talk, this study characterised synovial fluid EVs (SFEV...

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Principais autores: Caitlin Ditchfield, Joshua Price, Edward T. Davis, Simon W. Jones
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2025-06-01
Serier:Biomolecules
Fag:
osteoarthritis
extracellular vesicles
synovial fluid
articular chondrocytes
synovitis
Online adgang:https://www.mdpi.com/2218-273X/15/6/829
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