Consideration of Metabolite Efflux in Radiolabelled Choline Kinetics

Hypoxia is a complex microenvironmental condition known to regulate choline kinase α (CHKA) activity and choline transport through transcription factor hypoxia-inducible factor-1α (HIF-1α) and, therefore, may confound the uptake of choline radiotracer [¹⁸F]fluoromethyl-[1,2-²H<...

Fuld beskrivelse

Bibliografiske detaljer

Principais autores:	Yunqing Li, Marianna Inglese, Suraiya Dubash, Chris Barnes, Diana Brickute, Marta Costa Braga, Ning Wang, Alice Beckley, Kathrin Heinzmann, Louis Allott, Haonan Lu, Cen Chen, Ruisi Fu, Laurence Carroll, Eric O. Aboagye
Format:	Artigo
Sprog:	Inglês
Udgivet:	MDPI AG 2021-08-01
Serier:	Pharmaceutics
Fag:	choline kinase hypoxia efflux
Online adgang:	https://www.mdpi.com/1999-4923/13/8/1246
Tags:	Tilføj Tag Ingen Tags, Vær først til at tagge denne postø!