Physical exercise modulates plasma irisin levels in endurance athletes: Implications for Parkinson's disease

Physical exercise (PE) improves clinical outcomes in individuals with Parkinson's disease (PD) through unclear mechanisms. Irisin, a neuroprotective protein released by myocytes during PE, may play a role, but in vivo data in PD are limited. We investigated plasma irisin in a unique PD population en...

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Autores principales:	Piergiorgio Grillo, Deborah Di Martino, Alessandra Calculli, Roberto De Icco, Luca Martinis, Roberto Bottinelli, Simone Porcelli, Carlo Fazio, Davide Comolli, Federico Bighiani, Giulia Di Lazzaro, Jasmine Gambelli, Veronica Ghiglieri, Silvia Cerri, Paolo Calabresi, Michele Terzaghi, Antonio Pisani
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Elsevier 2025-10-01
Colección:	Neurobiology of Disease
Materias:	Parkinson's disease Irisin Physical exercise Endurance training Neuroprotection Biomarkers
Acceso en línea:	http://www.sciencedirect.com/science/article/pii/S0969996125002815
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