Unveiling the Multifaceted Roles of ISG15: From Immunomodulation to Therapeutic Frontiers

The Interferon Stimulated Gene 15 (ISG15), a unique Ubiquitin-like (Ubl) modifier exclusive to vertebrates, plays a crucial role in the immune system. Primarily induced by interferon (IFN) type I, ISG15 functions through diverse mechanisms: (i) covalent protein modification (ISGylation); (ii) non-co...

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Autors principals:	Enrique Álvarez, Michela Falqui, Laura Sin, Joseph Patrick McGrail, Beatriz Perdiguero, Rocío Coloma, Laura Marcos-Villar, Céline Tárrega, Mariano Esteban, Carmen Elena Gómez, Susana Guerra
Format:	Artigo
Idioma:	Inglês
Publicat:	MDPI AG 2024-02-01
Col·lecció:	Vaccines
Matèries:	IFN ISG15 ISGylation vaccines inflammation immunity
Accés en línia:	https://www.mdpi.com/2076-393X/12/2/153
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