Multi-organ single-cell analysis reveals PLD4 as a biomarker and potential therapeutic target of blastic plasmacytoid dendritic cell neoplasm

Abstract Background Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare hematological malignancy originating from precursors of plasmacytoid dendritic cells. This study aimed to understand the relationship between malignant clones in different tissues and determine new biomarkers to impro...

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Bibliografische Detailangaben

Hauptverfasser:	Meng Wang, Xiaotong Xue, Zhenzhen Wang, Chuan Wang, Gongqi Yu, Zihao Mi, Xu Sang, Jianwen Wang, Yongxia Liu, Xuechao Chen, Shengli Chen, Guizhi Zhou, Hong Liu, Hao Chen, Yonghu Sun, Furen Zhang
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	BMC 2025-11-01
Schriftenreihe:	Cancer Cell International
Schlagworte:	Blastic plasmacytoid dendritic cell neoplasm (BPDCN) PLD4 Single-cell analyses
Online-Zugang:	https://doi.org/10.1186/s12935-025-04038-9
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