Relationship of hypoxia-inducible factor 1α and p21<sup>WAF1/CIP1 </sup>expression to cell apoptosis and clinical outcome in patients with gastric cancer
<p>Abstract</p> <p>Background</p> <p>Hypoxia-inducible factor-1α (HIF-1α) plays an essential role in oxygen homeostasis. The expression of HIF-1α-inducible genes is associated with tumor progression. p21 mediates cell cycle arrest and is one of the downstream genes targeted by HIF-1.</p> <p>Patients...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BMC
2006-12-01
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| Serie: | World Journal of Surgical Oncology |
| Accesso online: | http://www.wjso.com/content/4/1/94 |
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