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Iodothyronine deiodinases and reduced sensitivity to thyroid hormones

Iodothyronine deiodinases are selenoproteins that regulate thyroid hormone metabolism. Of the three types of deiodinases, type 2 is the major regulator of intracellular triiodothyronine concentration in both the hypothalamus and pituitary, and therefore the major regulator of thyrotropin secretion....

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Rosa Maria Paragliola, Andrea Corsello, Paola Concolino, Francesca Ianni, Giampaolo Papi, Alfredo Pontecorvi, Salvatore Maria Corsello
Format: Artigo
Sprache:Inglês
Veröffentlicht: IMR Press 2020-01-01
Schriftenreihe:Frontiers in Bioscience-Landmark
Schlagworte:
iodothyronine deiodinases
thyroid hormone
hypothalamus–pituitary–thyroid axis
secisbp2
dio polymorphism
reduced sensitivity to thyroid hormone
review
Online-Zugang:https://www.imrpress.com/journal/FBL/25/2/10.2741/4803
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