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Vibrio pore-forming leukocidin activates pyroptotic cell death via the NLRP3 inflammasome

Cell death mechanisms are central to combat infections and to drive inflammation. The inflammasome controls infection through activation of caspase-1 leading to either IL-1β dependent inflammation, or pyroptotic cell death in infected cells. Hemolysins, which are pore-forming toxins (PFTs), alter th...

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Bibliografski detalji
Glavni autori: Hadar Cohen, Noam Baram, Liat Edry-Botzer, Ariel Munitz, Dor Salomon, Motti Gerlic
Format: Artigo
Jezik:Inglês
Izdano: Taylor & Francis Group 2020-01-01
Serija:Emerging Microbes and Infections
Teme:
Online pristup:https://www.tandfonline.com/doi/10.1080/22221751.2020.1720526
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