Circulating exosomal miR-550a-5p/miR-665 identify coronary microvascular dysfunction and drive endothelial–myocyte crosstalk in type 2 diabetes

ObjectiveThis study aimed to identify circulating exosomal microRNAs for early detection of coronary microvascular dysfunction (MD) and stratification of myocardial injury risk in type 2 diabetes, and to test whether miR-550a-5p derived from endothelial cell models mechanistically links endothelial...

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Detalles Bibliográficos

Principais autores:	Xiudong Ding, Guangliang Bai, Xin Liu, Yueming Dong, Yinghui Chai, Bing Han, Xianghong Meng, Hong Lei
Formato:	Artigo
Idioma:	Inglês
Publicado:	Frontiers Media S.A. 2026-01-01
Series:	Frontiers in Cell and Developmental Biology
Assuntos:	coronary microvascular dysfunction exosomes hippo–YAP signaling miR-550a-5p miR-665 type 2 diabetes
Acceso en liña:	https://www.frontiersin.org/articles/10.3389/fcell.2026.1744708/full
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