CD73 activity controls cytotoxic CD4 T-cell response driving myocardial pathology in chronic Chagas disease

Chagas disease, caused by Trypanosoma cruzi, is the major cause of infectious cardiopathology worldwide. Although cytotoxic CD4 T-cells (CD4 CTLs) have recently been recognized as crucial effectors in infections and inflammation, the mechanisms that control their differentiation and impact on pathol...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Gastón Bergero, Yanina L. Mazzocco, Zoé M. Cejas Gallardo, Walter Rivarola, Sebastian Del Rosso, Maria P. Aoki
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Frontiers Media S.A. 2026-05-01
Schriftenreihe:	Frontiers in Immunology
Schlagworte:	adenosine cardiomyopathy CD4 CTL granzyme B Trypanosoma cruzi infection immunoregulation
Online-Zugang:	https://www.frontiersin.org/articles/10.3389/fimmu.2026.1770276/full
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