Establishment of an in Vitro Human Blood-Brain Barrier Model Derived from Induced Pluripotent Stem Cells and Comparison to a Porcine Cell-Based System

The blood-brain barrier (BBB) is responsible for the homeostasis between the cerebral vasculature and the brain and it has a key role in regulating the influx and efflux of substances, in healthy and diseased states. Stem cell technology offers the opportunity to use human brain-specific cells to es...

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Detalhes bibliográficos

Principais autores:	Annalise Di Marco, Domenico Vignone, Odalys Gonzalez Paz, Ivan Fini, Maria Rosaria Battista, Antonella Cellucci, Elena Bracacel, Giulio Auciello, Maria Veneziano, Vinod Khetarpal, Mark Rose, Alessandro Rosa, Isabelle Gloaguen, Edith Monteagudo, Todd Herbst, Celia Dominguez, Ignacio Muñoz-Sanjuán
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2020-04-01
coleção:	Cells
Assuntos:	blood brain barrier human induced pluripotent stem cells CNS permeability Huntington’s disease
Acesso em linha:	https://www.mdpi.com/2073-4409/9/4/994
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