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Rethinking residual p53 function in HPV-positive cervical cancer cells

ABSTRACT Human papillomavirus (HPV)-driven cancers remain some of the most prevalent cancers globally. HPV E7 induces unscheduled cellular DNA replication in the infected cell; the resulting apoptotic signaling is counteracted by high-risk HPV E6 oncoprotein, which promotes cell proliferation by tar...

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Principais autores: Sannia Farrukh, Nezka Kavcic, Giulia Canarutto, Silvano Piazza, Lawrence Banks
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2026-06-01
Series:Journal of Virology
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Acceso en liña:https://journals.asm.org/doi/10.1128/jvi.00479-25
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