Green High-Yielding One-Pot Approach to Biginelli Reaction under Catalyst-Free and Solvent-Free Ball Milling Conditions

A simple, green, and efficient approach was used to synthesize 3,4-dihydropyrimidines derivatives. We showed that the application of the planetary ball milling method with a ball-to-reagent weight ratio of 8 for the Biginelli reaction provides 3,4-dihydropyrimidines derivatives with excellent yields...

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Principais autores:	Mohamed Ould M’hamed, Abdulrahman G. Alshammari, O. M. Lemine
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2016-12-01
coleção:	Applied Sciences
Assuntos:	Biginelli reaction ball milling catalyst-free solvent-free dihydropyrimine derivatives
Acesso em linha:	http://www.mdpi.com/2076-3417/6/12/431
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