Regulatory B cell expansion and type 1 innate lymphoid cell suppression characterise immune modulation in paediatric lupus nephritis

Objective B-cell activating factor (BAFF) is essential for B-cell survival and innate immune activation, and its dysregulation contributes to the pathogenesis of lupus nephritis (LN). This study investigated whether BAFF-pathway inhibition alters the balance between regulatory B cells (Bregs) and ty...

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Autori principali:	Chang-Ching Wei, Kuender D Yang, Ching-Yuang Lin, Jien-Wen Chien, Tzu-Cheng Su, Kan-Hsuan Lin, Kai-Hung Hsiao, Ya-Chih Tien, Lin-Shien Fu, Jun-Kai Kao, Yi-Giien Tsai
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	BMJ Publishing Group 2026-05-01
Serie:	RMD Open
Accesso online:	https://rmdopen.bmj.com/content/12/2/e006492.full
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