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AlphaFold2 assists in providing novel mechanistic insights into the interactions among the LUBAC subunits

The linear ubiquitin chain assembly complex (LUBAC) is the only known E3 ligase complex in which the ubiquitin-like (UBL) domains of SHARPIN and HOIL-1L interact with HOIP to determine the structural stability of LUBAC. The interactions between subunits within LUBAC have been a topic of extensive re...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Wang Chenchen, Gu Chunying, Lv Ying, Liu Hongyu, Wang Yanan, Zuo Yongmei, Jiang Guangyu, Liu Lili, Liu Jiafu
Hōputu: Artigo
Reo:Inglês
I whakaputaina: China Science Publishing & Media Ltd. 2024-04-01
Rangatū:Acta Biochimica et Biophysica Sinica
Ngā marau:
Urunga tuihono:https://www.sciengine.com/doi/10.3724/abbs.2024047
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