The Impact of Aging on Brain Pituitary Adenylate Cyclase Activating Polypeptide, Pathology and Cognition in Mice and Rhesus Macaques

Pituitary adenylate cyclase activating polypeptide (PACAP) is associated with Alzheimer’s disease (AD), but its age-related effects are unknown. We chose the rhesus macaque due to its closeness to human anatomy and physiology. We examined four variables: aging, cognitive performance, amyloid plaques...

Täydet tiedot

Bibliografiset tiedot

Päätekijät:	Pengcheng Han, Megan Nielsen, Melissa Song, Junxiang Yin, Michele R. Permenter, Julie A. Vogt, James R. Engle, Brittany N. Dugger, Thomas G. Beach, Carol A. Barnes, Jiong Shi
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	Frontiers Media S.A. 2017-06-01
Sarja:	Frontiers in Aging Neuroscience
Aiheet:	Alzheimer’s disease PACAP aging nonhuman primates
Linkit:	http://journal.frontiersin.org/article/10.3389/fnagi.2017.00180/full
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