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Directed and efficient generation of calretinin interneurons from human pluripotent stem cells

Abstract Background Schizophrenia, autism, and epilepsy are associated with dysfunctions in cortical GABAergic interneurons. Calretinin-expressing interneurons, the most prominent type, constitute approximately 50% of human cortical GABAergic neurons and are closely linked to cognition. However, the...

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Autores principales: Xuewei Du, Renli Qi, Congge Li, Wenpei Zhou, Shijiao Wang, Shenxing Wei, Runzhong Wu, Yu Yin, Tianqing Li, Xiaoqing Zhu
Formato: Artigo
Lenguaje:Inglês
Publicado: BMC 2025-08-01
Colección:Stem Cell Research & Therapy
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Acceso en línea:https://doi.org/10.1186/s13287-025-04603-z
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